Opportunity Information: Apply for RFA DA 24 037
Accelerating the Pace of Drug Abuse Research Using Existing Data (R21 Clinical Trial Optional) is a National Institutes of Health (NIH) funding opportunity (RFA-DA-24-037) that supports short, exploratory research projects that make creative, rigorous use of data that already exist. Instead of funding new data collection as the central activity, this announcement is designed to speed up progress by encouraging investigators to extract more value from public-use datasets and other extant community-based or clinical data resources, including social science, behavioral, administrative, and neuroimaging datasets. The overall aim is to generate new insights efficiently by applying innovative questions and analytic approaches to data that have already been gathered, curated, or archived.
The scientific focus is broad but clearly centered on drug use behaviors and related outcomes. In this context, "drug use" is defined expansively to include alcohol, tobacco, prescription drugs, and other drugs. Projects are expected to advance understanding of etiology and epidemiology, meaning they should help clarify why drug use and substance-related problems emerge, how they spread or cluster across populations, and how patterns change over time. The FOA also emphasizes research on trajectories of use (for example, initiation, escalation, remission, relapse, and long-term patterns) and the consequences of drug use, including morbidity and mortality. Beyond substance use itself, applications can address prevention of drug use and HIV and can investigate health service utilization, such as access to care, treatment engagement, retention, quality of services, outcomes, and system-level factors that shape prevention and treatment delivery.
A key theme is leveraging existing datasets to study risk and resilience, including how protective factors buffer individuals and communities against developing substance use disorders or related psychopathology. This includes research that links substance use to mental health outcomes, comorbidity, developmental pathways, and social determinants of health. The announcement also encourages studies that can inform practical strategies to guide the development, testing, implementation, and delivery of services that are high quality, effective, and efficient for preventing and treating drug abuse and HIV. In other words, the program is not only about describing problems; it is also about producing evidence that can improve real-world prevention and treatment systems, often by analyzing data that reflect routine practice, administrative records, or large community and clinical cohorts.
The mechanism is an NIH R21, which typically supports early-stage, proof-of-concept, or high-impact exploratory work. The FOA is labeled "Clinical Trial Optional," indicating that applicants may propose a clinical trial if it fits the project, but a trial is not required and many competitive applications will instead rely on secondary analysis of existing data. The listed award ceiling is $275,000, reflecting the small, targeted nature of R21 projects. The opportunity is categorized as a discretionary grant within the education and health activity area, under CFDA number 93.279.
Eligibility is intentionally broad, spanning many sectors and organization types. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized tribal governments; public housing and Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; and small businesses. The FOA also explicitly highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations). This wide eligibility signals an interest in diverse perspectives, interdisciplinary teams, and research contexts that can better address substance use and HIV prevention needs across different populations and settings.
Key dates and administrative details provided include an original closing date of 2024-11-15 and a creation date of 2023-02-07. In practical terms, the opportunity is best suited for investigators who already have access to strong existing datasets (or can obtain access quickly), have a compelling, novel research question, and can use advanced or innovative analytic methods to produce timely findings that improve understanding of substance use behaviors, related disorders, HIV prevention, and the prevention and treatment service landscape.Apply for RFA DA 24 037
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Accelerating the Pace of Drug Abuse Research Using Existing Data (R21 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
- This funding opportunity was created on 2023-02-07.
- Applicants must submit their applications by 2024-11-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $275,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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