Opportunity Information: Apply for HRSA 21 104
The Regional Pediatric Pandemic Network grant opportunity (HRSA-21-104) is a discretionary cooperative agreement offered by the U.S. Department of Health and Human Services through the Health Resources and Services Administration (HRSA). Its core aim is to strengthen how the United States prepares for and responds to future pandemics and other major global health threats specifically as they affect children. The program is built around the idea that pediatric readiness cannot be an afterthought in emergency response systems, so it focuses on organizing and aligning children’s hospitals, pediatric clinicians, and community partners to deliver coordinated, research-informed pediatric care during fast-moving public health emergencies.
The program would establish a single national “Network” made up of five children’s hospitals (or their affiliated university pediatric partners) located in geographically diverse regions of the country. These five institutions are expected to function as a collaborative, cross-institution team rather than as five separate projects. The work emphasizes planning and implementation under a cooperative agreement structure, meaning HRSA would have substantial involvement in guiding, coordinating, and supporting the Network’s activities rather than simply issuing funds with minimal federal engagement. A major deliverable implied by the notice is the ability to coordinate preparation and response activities and to provide real-time dissemination of pediatric clinical guidance and practices that are informed by research and current evidence as conditions evolve during a crisis.
A central feature of the opportunity is broad coordination beyond the five anchor institutions. The Network is expected to connect the Nation’s children’s hospitals and other pediatric experts and to strengthen partnerships with existing emergency preparedness systems at local, state, regional, and national levels. In practice, this means aligning pediatric-focused expertise with established preparedness and response infrastructures so that plans, protocols, communication pathways, and operational decisions account for children’s medical and public health needs. The notice highlights that the goal is to ensure that preparedness and response activities explicitly address the needs of all children, reflecting the reality that pediatric populations have different clinical, logistical, and support requirements than adult populations during emergencies.
Funding is structured as one award with an award ceiling of $9,700,000. Although the Network includes five institutions, only one organization serves as the primary recipient and is listed as the grantee of record on the Notice of Award. The application, however, must present a proposal that supports and clearly identifies all five participating children’s hospitals or affiliated university pediatric partners, and together they must meet the eligibility criteria described in the opportunity’s eligibility section. The eligibility field is listed as “Others,” with additional clarification provided in the full opportunity text, signaling that applicants must closely follow the specific requirements about who can apply and how the five-institution Network must be constituted.
Key administrative details include the program’s identification under CFDA 93.110, with the funding opportunity created on May 6, 2021 and an original closing date of July 8, 2021. Overall, the grant is designed to build a coordinated pediatric pandemic preparedness and response capability by organizing a national, regionally distributed set of leading pediatric institutions, integrating them with existing emergency systems, and enabling rapid, evidence-based pediatric guidance and support during future public health emergencies.Apply for HRSA 21 104
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Regional Pediatric Pandemic Network" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.110.
- This funding opportunity was created on May 06, 2021.
- Applicants must submit their applications by Jul 08, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $9,700,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Regional Pediatric Pandemic Network (HRSA-21-104) - Frequently Asked Questions
1) What is the Regional Pediatric Pandemic Network grant (HRSA-21-104)?
The Regional Pediatric Pandemic Network (HRSA-21-104) is a discretionary cooperative agreement grant opportunity offered by the U.S. Department of Health and Human Services (HHS) through the Health Resources and Services Administration (HRSA). It is designed to strengthen how the United States prepares for and responds to future pandemics and other major global health threats as they affect children.
2) What is the main purpose of this program?
The core aim is to improve pediatric pandemic preparedness and response by organizing and aligning children's hospitals, pediatric clinicians, and community partners so they can deliver coordinated, research-informed pediatric care during fast-moving public health emergencies.
3) Why does the opportunity emphasize pediatric readiness?
The program is based on the idea that pediatric readiness should not be an afterthought in emergency response systems. It emphasizes planning and coordination that explicitly accounts for children's medical and public health needs, which can differ from adult needs during emergencies.
4) What will be created or established through this award?
The award is intended to establish a single national "Network" made up of five children's hospitals (or their affiliated university pediatric partners) located in geographically diverse regions of the country.
5) How many awards will HRSA make under this opportunity?
Funding is structured as one award. Even though the Network includes five institutions, a single organization serves as the primary recipient and is the grantee of record on the Notice of Award.
6) How much funding is available?
The award ceiling is $9,700,000 for the single award described in the opportunity information provided.
7) If the Network includes five institutions, why is there only one grantee of record?
Under this structure, only one organization is designated as the primary recipient and will be listed as the grantee of record on the Notice of Award. The application must still clearly identify and support all five participating institutions as part of the proposed national Network.
8) What types of institutions can be part of the five-institution Network?
The Network is described as consisting of five children's hospitals or their affiliated university pediatric partners. The application must identify all five participants and indicate that, together, they meet the eligibility criteria described in the opportunity.
9) What does the eligibility category "Others" mean in this notice?
The eligibility field is listed as "Others," with additional clarification provided in the full opportunity text. Based on the information provided, this signals that applicants need to follow the specific eligibility requirements in the opportunity's eligibility section, including requirements about how the five-institution Network must be constituted.
10) Is this grant a standard grant or a cooperative agreement?
It is a discretionary cooperative agreement. That means HRSA is expected to have substantial involvement in guiding, coordinating, and supporting the Network's activities rather than simply providing funds with minimal federal engagement.
11) What does "substantial involvement" from HRSA imply for the funded Network?
Based on the description, HRSA will play an active role in guiding, coordinating, and supporting activities. The Network should expect collaboration with HRSA as the work is planned and implemented, rather than operating independently with limited federal interaction.
12) Are the five institutions expected to operate independently or as a unified team?
They are expected to function as a collaborative, cross-institution team rather than as five separate projects.
13) What kinds of activities or outcomes are emphasized?
The work emphasizes coordinated preparation and response activities for pediatric emergencies and the ability to provide real-time dissemination of pediatric clinical guidance and practices informed by research and current evidence as conditions evolve during a crisis.
14) What is meant by "real-time dissemination" of pediatric clinical guidance?
The notice implies the Network should be able to share pediatric clinical guidance and practices quickly as a public health emergency unfolds, and to ensure that guidance reflects research and current evidence as conditions change.
15) Who is the Network expected to coordinate with beyond the five anchor institutions?
The Network is expected to connect the Nation's children's hospitals and other pediatric experts, and to strengthen partnerships with existing emergency preparedness systems at local, state, regional, and national levels.
16) What does it mean to align with existing emergency preparedness systems?
In practice, it means integrating pediatric-focused expertise with established preparedness and response infrastructure so that plans, protocols, communication pathways, and operational decisions account for children's needs during emergencies.
17) How does this program address the needs of children differently than adult-focused response systems?
The notice highlights that preparedness and response activities should explicitly address the needs of all children, recognizing that pediatric populations have different clinical, logistical, and support requirements than adult populations during emergencies.
18) Is the Network intended to be regional or national?
It is a single national Network that is regionally distributed across five geographically diverse regions through five children's hospitals (or affiliated university pediatric partners).
19) What is the CFDA number associated with this opportunity?
The program is identified under CFDA 93.110.
20) When was this funding opportunity created, and what was the original closing date?
The funding opportunity was created on May 6, 2021, and the original closing date was July 8, 2021.
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