Opportunity Information: Apply for PA 21 199
The National Institutes of Health (NIH) is soliciting applications under PA 21-199, Research on Autism Spectrum Disorders (R03 Clinical Trial Optional), a reissue of PA-18-399. This funding opportunity is aimed at supporting focused research that helps clarify Autism Spectrum Disorders (ASD), specifically work that improves understanding of ASD causes (etiology), how ASD occurs and is distributed across populations (epidemiology), how ASD is identified and assessed (diagnosis), and how services are best organized and delivered to people with ASD and their families (optimal means of service delivery). The announcement is deliberately broad to encourage a range of projects that can move the field forward, especially in areas where a smaller, targeted study can produce useful evidence, methods, or early findings that justify later, larger-scale research.
The mechanism is the NIH R03, which is designed for small, discrete, well-defined projects. A key point is that R03 projects are meant to be completed within two years and with limited resources. In practical terms, that means applicants are expected to propose tightly scoped aims rather than large multi-site trials or sprawling programs of research. Because of the R03 format, applications are also not expected to include lengthy narratives or extensive preliminary justification. Importantly, preliminary data are not required, which lowers the barrier for early-stage ideas, pilot projects, and feasibility work, particularly when the goal is to test whether a method, recruitment approach, measurement strategy, or analytic plan is workable before investing in a larger study.
The FOA highlights several types of projects that fit especially well. These include developing or refining research methodologies or technologies relevant to ASD research, conducting secondary analyses of existing datasets (for example, reanalyzing previously collected clinical, educational, administrative, or population data to answer new ASD-related questions), and running pilot or feasibility studies to establish whether a proposed approach is practical and informative. Because clinical trials are listed as optional, applicants may propose studies that do or do not meet the definition of a clinical trial, provided the work aligns with the scientific goals around ASD etiology, epidemiology, diagnosis, or service delivery.
Eligibility is expansive and includes a wide range of public, private, nonprofit, and governmental entities. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other organizations. The opportunity also explicitly calls out additional eligible groups such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations). This breadth signals NIH interest in encouraging ASD research capacity across many settings, including community and service systems where questions about diagnosis and service delivery are often most directly observed.
From the posted summary details, the opportunity is categorized as a discretionary grant program within the broad activity area of environment, health, income security, and social services, and it is associated with CFDA numbers 93.113, 93.173, 93.242, and 93.865. The listed award ceiling is $50,000. The original closing date shown is 2024-11-16. Overall, this FOA is best suited to applicants who have a clearly defined ASD-related research question that can be answered with a modest budget and a two-year timeline, especially when the project’s main value is generating early evidence, testing feasibility, advancing measurement or analytic approaches, or leveraging existing data to deliver timely findings.Apply for PA 21 199
- The National Institutes of Health in the environment, health, income security and social services sector is offering a public funding opportunity titled "Research on Autism Spectrum Disorders (R03 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.173, 93.242, 93.865.
- This funding opportunity was created on 2021-03-31.
- Applicants must submit their applications by 2024-11-16. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 21 199) also looked into and applied for these:
| Funding Opportunity |
|---|
| Autism Centers of Excellence: Centers (P50 Clinical Trial Optional) Apply for RFA HD 22 008 Funding Number: RFA HD 22 008 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| Autism Centers of Excellence: Networks (R01 Clinical Trial Optional) Apply for RFA HD 22 007 Funding Number: RFA HD 22 007 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional) Apply for PAR 21 319 Funding Number: PAR 21 319 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional) Apply for PAR 21 311 Funding Number: PAR 21 311 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional) Apply for PAR 22 098 Funding Number: PAR 22 098 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional) Apply for PAR 22 097 Funding Number: PAR 22 097 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed) Apply for PAR 23 171 Funding Number: PAR 23 171 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Implementation Research on Noncommunicable Disease Risk Factors among Low- and Middle-Income Country and Tribal Populations Living in City Environments (R01 Clinical Trial Optional) Apply for PAR 23 319 Funding Number: PAR 23 319 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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